Pilot Program

 

Current Grants
Name
Project Title
Banfi, Botond, Ph.D.
Thiocyanate Secretion-Dependent Oxidative Host Defense in CF and Health Airways
Cornell, Robert, Ph.D.
Generation of a Transgenic Zebrafish for Optimization of Gene Correction Methodologies
Keshavje, Shaf, M.D.
Repair of Damaged Lungs for Transplantation Using and Ex-vivo Gene Therapeutic Surgery
Raikwar, Sudhanshu, Ph.D.
Deviation of Insulin-Producing Cells from ES Cells

Past Grants
Name
Project Title
Long Term Gene Expression by Epidermal Stem Cells
Cheng, Pi-Wan, Ph.D.
Ciliated Cell-Specific Gene Transfer
Retroviral Gene Transfer to Airway Epithelia with MMLV-based Vectors
Modified Antisense Oligonucleotides as Pseudomonas Antimicrobials
Duan, Dongsheng, Ph.D.
Analysis of rAAV Integration Specificity
Dunnwald, Martine, Ph.D.
Epidermal Stem Cells as a Gene Delivery System
Circular Intermediates of rAAV as Novel Gene Transfer Vectors
Gene Transfer into Spiral Ganglion Neurons in vivo
Harper, Scott, Ph.D.
Autoregulated AAV Vectors for Inducible RNA Interference
Henry, Michael, Ph.D.
Cellular Uptake and in vivo Pharmacodynamics of Cholesterol-siRNAs
Targeted Modulation of Vasopressin in Brain Magnocellular Neurons by Adenovirus-Mediated Gene Therapy
Jones, Bradley, Ph.D.
Gene Therapy for Phenylketonuria using an Adherent Bacterial Vector
Kang, Yubin, Ph.D.
Hematopoietic Stem Cell Gene Transfer for Hemophilia A
Reversibly Immortal Human Airway Epithelium
Role of CPG Motifs in Plasmid DNA as a Barrier to Gene Transfer
Krieg, Arthur, M.D.
Development of Non-Immune Activating Gene Therapy Vectors for Cystic Fibrosis
Site-Directed Mutation of ES Cells by Oligonucleotides
Liang, Luchuan, Ph.D.
A Study of Epidermal Stem Cells in the Airway
Adenoviral Mechanisms for Inhibition of Interferon Signal Transduction
Lotery, Andrew, M.D.
Development of Gene Therapy for Batten Disease
Zinc Finger Nucleases Targeting Hepatitis B Virus DNAs
Optimization of Retroviral Vectors for Mucosal Delivery
Evaluating Gene Therapy Using a Fluorescent Marker
The CCT Promoter to Drive High-Level Expression of CFTR
AAV-Associated Cluster Contrast Agents for MR/CT Imaging of Vector Biodistribution
Optimization of the CFTR Coding Sequence for Efficient Packaging into the AAV Vector
Reversibly PEGylated Gene Delivery Particles for Treating Cystic Fibrosis
Cell-Specific Targeting of Herpes Simplex Virus in Gene Therapy for Cystic Fibrosis
Sanders, David A, Ph.D.
Direct Gene Transfer to Intact Airway Epithelia for CF
Singh, Pradeep, M.D.
CFTR-Mediatred Gene Correction of Biofilm Formation in the CF Airway
Targeted Integration of a Lentiviral Vector
A GBV-C Gene Therapy Vector for Cystic Fibrosis
Stecenko, Arlene, M.D.
Delivery of CFTR Protein Using membrane Translocating Sequences
Transgene Tolerance: a Role for Apoptosis
Stipp, Christopher, Ph.D.
Enhancing the Neurite Outgrowth Potential of Neuronal Precursor Cells
Goblet Cell Hyperplasia and Gene Transfer in CF
Site Directed Mutagenesis Using Triplex Target Sites
Modification of the Cell Surface to Aid Gene Transfer
Harmful Effects of Integrating AAV Vectors
Hybrid rAAV Genomes for Gene Therapy of Cystic Fibrosis
Study of Chimera Recombinant Adenovirus