Pilot Program
Current Grants |
|
Name |
Project Title |
| Fiegel, Jennifer, Ph.D. | Development of LOS-Modified Nanoparticles for Improved Airway Epithelial Uptake |
| Grangrande, Paloma, Ph.D. | RNA Aptamers for Cytoplasmic Delivery of Nucleic Acids |
| Liu, Xiaoming, Ph.D. | High-Level Ectopic Expression of CFTR Imposes a Selective Disadvantage to Airway Epithelial Stem/Progenitor Cells |
| Maury, Wendy, Ph.D. | Development of Highly Transducing Glycoproteins for Transgene Delivery Into Airway Epithelial Cells |
| Parekh, Kalpaj, M.D. | Epithelial Stem Cells in a Lung Transplant Model |
Raikwar, Sudhanshu, Ph.D. |
Deviation of Insulin-Producing Cells from ES Cells |
Past Grants |
|
Name |
Project Title |
Banfi, Botond, Ph.D. |
Thiocyanate Secretion-Dependent Oxidative Host Defense in CF and Health Airways |
Long Term Gene Expression by Epidermal Stem Cells |
|
Cheng, Pi-Wan, Ph.D. |
Ciliated Cell-Specific Gene Transfer |
Cornell, Robert, Ph.D. |
Generation of a Transgenic Zebrafish for Optimization of Gene Correction Methodologies |
Davidson, Beverly, Ph.D. |
Retroviral Gene Transfer to Airway Epithelia with MMLV-based Vectors |
Dagle, John M., Ph.D. |
Modified Antisense Oligonucleotides as Pseudomonas Antimicrobials |
Duan, Dongsheng, Ph.D. |
Analysis of rAAV Integration Specificity |
| Dunnwald, Martine, Ph.D. |
Epidermal Stem Cells as a Gene Delivery System |
Engelhardt, John F., Ph.D. |
Circular Intermediates of rAAV as Novel Gene Transfer Vectors |
Green, Steven H., Ph.D. |
Gene Transfer into Spiral Ganglion Neurons in vivo |
Harper, Scott, Ph.D. |
Autoregulated AAV Vectors for Inducible RNA Interference |
Henry, Michael, Ph.D. |
Cellular Uptake and in vivo Pharmacodynamics of Cholesterol-siRNAs |
Johnson, Alan, Ph.D. |
Targeted Modulation of Vasopressin in Brain Magnocellular Neurons by Adenovirus-Mediated Gene Therapy |
Jones, Bradley, Ph.D. |
Gene Therapy for Phenylketonuria using an Adherent Bacterial Vector |
Kang, Yubin, Ph.D. |
Hematopoietic Stem Cell Gene Transfer for Hemophilia A |
Keshavje, Shaf, M.D. |
Repair of Damaged Lungs for Transplantation Using and Ex-vivo Gene Therapeutic Surgery |
Klingelhutz, Aloysius J., Ph.D. |
Reversibly Immortal Human Airway Epithelium |
Kline, Joel, M.D. |
Role of CPG Motifs in Plasmid DNA as a Barrier to Gene Transfer |
Krieg, Arthur, M.D. |
Development of Non-Immune Activating Gene Therapy Vectors for Cystic Fibrosis |
Lamb, Fred, S., M.D., Ph.D. |
Site-Directed Mutation of ES Cells by Oligonucleotides |
Liang, Luchuan, Ph.D. |
A Study of Epidermal Stem Cells in the Airway |
Look, Dwight C., M.D. |
Adenoviral Mechanisms for Inhibition of Interferon Signal Transduction |
Lotery, Andrew, M.D. |
Development of Gene Therapy for Batten Disease |
McCaffrey, Anton, Ph.D. |
Zinc Finger Nucleases Targeting Hepatitis B Virus DNAs |
McCray, Paul, M.D. |
Optimization of Retroviral Vectors for Mucosal Delivery |
McLennan, Geoffrey, Ph.D. |
Evaluating Gene Therapy Using a Fluorescent Marker |
Mallampalli, Rama, M.D. |
The CCT Promoter to Drive High-Level Expression of CFTR |
Messerle, Louis, Ph.D. |
AAV-Associated Cluster Contrast Agents for MR/CT Imaging of Vector Biodistribution |
| Ostedgaard, Lynda S., Ph.D. | Optimization of the CFTR Coding Sequence for Efficient Packaging into the AAV Vector |
Rice, Kevin, Ph.D. |
Reversibly PEGylated Gene Delivery Particles for Treating Cystic Fibrosis |
Roller, Richard, Ph.D. |
Cell-Specific Targeting of Herpes Simplex Virus in Gene Therapy for Cystic Fibrosis |
Sanders, David A, Ph.D. |
Direct Gene Transfer to Intact Airway Epithelia for CF |
Singh, Pradeep, M.D. |
CFTR-Mediatred Gene Correction of Biofilm Formation in the CF Airway |
Sinn, Patrick, Ph.D. |
Targeted Integration of a Lentiviral Vector |
Stapleton, Jack, M.D. |
A GBV-C Gene Therapy Vector for Cystic Fibrosis |
Stecenko, Arlene, M.D. |
Delivery of CFTR Protein Using membrane Translocating Sequences |
Stein, Colleen S., Ph.D. |
Transgene Tolerance: a Role for Apoptosis |
Stipp, Christopher, Ph.D. |
Enhancing the Neurite Outgrowth Potential of Neuronal Precursor Cells |
Goblet Cell Hyperplasia and Gene Transfer in CF |
|
Weeks, Daniel, Ph.D. |
Site Directed Mutagenesis Using Triplex Target Sites |
Wiemer, DAvid, Ph.D. & Welsh, Michael, M.D., Co-PI |
Modification of the Cell Surface to Aid Gene Transfer |
Wu, Chun-Fang, Ph.D. |
Harmful Effects of Integrating AAV Vectors |
Yan, Ziying, Ph.D. |
Hybrid rAAV Genomes for Gene Therapy of Cystic Fibrosis |
Zabner, Joseph, M.D. |
Study of Chimera Recombinant Adenovirus |

